Fig. 5

Relationship between the ADCmean and OS for patients who underwent CRS, with or without HIPEC. Spearman’s correlation plots showed that the ADCmean was trended to positively associate with the OS period in all patients (a) and in the CRS + HIPEC (b) and CRS groups (c), with the correlation coefficient rho (R) values of 0.361, 0.369, and 0.192, respectively. Kaplan–Meier analysis indicated that patients with ADCmean ≤ 1.39 × 10− 3 mm2/s had significantly shorter OS periods than those with ADCmean > 1.39 × 10− 3 mm2/s in all patients (HR = 2.11, P = 0.001) (d) and in CRS + HIPEC (HR = 2.18, P = 0.010) (e) and CRS groups (HR = 2.48, P = 0.019) (f). ADC, apparent diffusion coefficient; ADCmean, mean ADC; CRS, cytoreductive surgery; HIPEC, hyperthermic intraperitoneal chemotherapy