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Table 4 Logistic regression analysis of risk factors affecting the incidence of ICIs-related myocarditis

From: Immune checkpoint inhibitor-related myocarditis in patients with lung cancer

Factors

Univariable

 

Multivariable

Hazard Ratio

(95% CI)

P Value

 

Hazard Ratio

(95% CI)

P Value

Age ≥ 70

0.4(0.19–0.89)

0.025

 

0.4(0.16–0.84)

0.018

BMI ≥ 24

1.0(0.48–1.86)

0.808

   

Male

0.4(0.14–0.97)

0.044

 

0.5(0.16–1.53)

0.225

Smoke

0.6(0.25–1.35)

0.204

   

NSCLC

0.4(0.16–0.85)

0.019

   

IV stage

1.3(0.57–3.10)

0.518

   

PD1

0.3(0.13–0.89)

0.028

 

0.4(0.13–0.97)

0.043

Combined ICI

1.5(0.68–4.27)

0.369

   

Cardiovascular history

1.2(0.64–2.53)

0.601

   

Diabetes Mellitus

0.8(0.33–2.34)

0.628

   
  1. BMI, body mass index; NSCLC, non-small cell lung cancer; PD-1, anti-programmed death-1; ICI, immune checkpoint inhibitors