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Fig. 3 | BMC Cancer

Fig. 3

From: Integrative analysis of a novel signature incorporating metabolism and stemness-related genes for risk stratification and assessing clinical outcomes and therapeutic responses in lung adenocarcinoma

Fig. 3

The metabolism and stemness-related gene signature and prognostic classifier in the LUAD cohort. A LASSO coefficient analysis of the metabolism and stemness-related DEGs is presented. The dotted lines in the graph indicate the values selected through 3-fold cross-validation. B A three-fold cross-validation is performed to determine the tuning parameter in the LASSO model, with partial likelihood deviation values plotted against log(λ), and the error bars representing standard error (SE). C A forest plot displays the hazard ratios for five metabolism and stemness-related prognostic DEGs obtained from multivariate Cox regression analyses. D, G Kaplan-Meier plot analyses are shown for the TCGA cohort (D) and the GEO-merged cohort (G). E, H The risk distribution among patients is depicted in the training cohort (E) and the GEO-merged cohort (H). F, I The ROC curves of the risk signature are illustrated for the training cohort (F) and the GEO-merged cohort (I). DEGs refers to differentially expressed genes

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BMC Cancer

ISSN: 1471-2407

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