Table 1 Clinical information of the study participants in the discovery and validation stages
From: A novel serum protein biomarker for the late-stage diagnosis of nasopharyngeal carcinoma
Characteristics | Discovery | Validation in HC and LNPC | Validation in ENPC and LNPC | ||||
|---|---|---|---|---|---|---|---|
HC(n = 5) | ENPC(n = 5) | LNPC(n = 5) | HC(n = 34) | LNPC(n = 34) | ENPC(n = 31) | LNPC(n = 75) | |
Age (years) | |||||||
Median | 45 | 43 | 46 | 50 | 44 | 50 | 49 |
(min–max) | (35–53) | (33–52) | (34–60) | (40–64) | (6–67) | (33–65) | (25–71) |
Sex | |||||||
Male | 5 | 5 | 5 | 17 | 17 | 23 | 55 |
Female | 0 | 0 | 0 | 17 | 17 | 8 | 20 |
VCA-IgA (1:X) | |||||||
+ (≥ 1:40) | 0 | 4 | 5 | 0 | 28 | 15 | 64 |
- (< 1:40) | 5 | 1 | 0 | 34 | 6 | 16 | 11 |
EBV DNA (copy/ml) | |||||||
+ (≥ 100) | - | 1 | 5 | - | 22 | 5 | 58 |
- (< 100) | - | 4 | 0 | - | 12 | 26 | 17 |