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Table 5 Risk of anxiety disorder by demographics among individuals with cancer

From: Bidirectional relationship between anxiety disorder and cancer: a longitudinal population-based cohort study

Variable

Anxiety

Cases

PY

Incidence

CHR (95% CI)

AHR (95% CI)

All

     

 Cancer free

14,087

1420588.57

0.99

ref

ref

 Cancer

2613

203262.40

1.29

1.30 (1.25–1.36)**

1.63 (1.56–1.71)**

Age (years)

     

< 30

     

 Cancer free

297

57848.59

0.51

ref

ref

 Cancer

101

11436.06

0.88

1.74 (1.39–2.18)**

1.81 (1.38–2.37)**

30–44

     

 Cancer free

2032

300535.67

0.68

ref

ref

 Cancer

596

51080.13

1.17

1.75 (1.60–1.92)**

1.92 (1.73–2.14)**

45–64

     

 Cancer free

6887

648669.69

1.06

ref

ref

 Cancer

1291

92827.35

1.39

1.32 (1.24–1.40)**

1.51 (1.42–1.61)**

≥ 65

     

 Cancer free

4871

413534.62

1.18

ref

ref

 Cancer

625

47918.86

1.30

1.09 (1.00-1.18)

1.36 (1.25–1.49)**

Sex

     

Female

     

 Cancer free

8594

730867.44

1.18

ref

ref

 Cancer

1727

118647.17

1.46

1.24 (1.18–1.31)**

1.59 (1.51–1.68)**

Male

     

 Cancer free

5493

689721.13

0.80

ref

ref

 Cancer

886

84615.23

1.05

1.31 (1.22–1.41)**

1.70 (1.57–1.83)**

CCI

     

< 3

     

 Cancer free

9104

818624.36

1.11

ref

ref

 Cancer

878

43079.45

2.04

1.77 (1.65–1.90)**

1.92 (1.79–2.05)**

≥ 3

     

 Cancer free

4983

601964.21

0.83

ref

ref

 Cancer

1735

160182.95

1.08

1.43 (1.35–1.51)**

1.46 (1.38–1.55)**

Urbanization level

     

Urban

     

 Cancer free

5573

565360.05

0.99

ref

ref

 Cancer

1067

84525.56

1.26

1.29 (1.20–1.37)**

1.62 (1.51–1.73)**

Suburban

     

 Cancer free

2983

307769.87

0.97

ref

ref

 Cancer

519

41462.44

1.25

1.29 (1.18–1.42)**

1.62 (1.47–1.79)**

Rural

     

 Cancer free

5531

547458.65

1.01

ref

ref

 Cancer

1027

77274.39

1.33

1.32 (1.24–1.41)**

1.66 (1.55–1.78)**

  1. Incidence: incidence density (100 per person-years)
  2. *: p <.05, **: p <.001, CHR: crude hazard ratio, AHR: adjusted hazard ratio controlling for age, sex, income, region, urbanization level, and CCI score, CCI: Charlson comorbidity index, CI: confidence interval, PY: person-years