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Table 3 Risk of cancer by type among individuals with anxiety disorder

From: Bidirectional relationship between anxiety disorder and cancer: a longitudinal population-based cohort study

Variable

Patients with anxiety

Patients without anxiety

Hazard ratio and 95% CI

Cases

Incidence a

Cases

Incidence a

CHR (95 CI%)

AHR (95 CI%)

Cancer type

      

 Colon cancer

353

0.14

1458

0.14

1.06 (0.94–1.19)

1.18 (1.05–1.33)*

 Lung cancer

324

0.13

1237

0.12

1.15 (1.01–1.29)*

1.24 (1.09–1.40)**

 Breast cancer

284

0.18

1123

0.16

1.12 (0.98–1.28)

1.27 (1.11–1.46)**

 Liver cancer

336

0.14

1072

0.10

1.36 (1.20–1.53)**

1.19 (1.05–1.35)*

 Oral cancer

103

0.04

475

0.04

0.92 (0.74–1.13)

1.07 (0.86–1.34)

 Prostate cancer

121

0.14

294

0.08

1.77 (1.43–2.19)**

1.97 (1.59–2.47)**

 Thyroid cancer

75

0.03

165

0.02

2.02 (1.54–2.66)**

2.13 (1.60–2.82)**

 Skin cancer

89

0.04

224

0.02

1.77 (1.38–2.27)**

2.10 (1.63–2.71)**

 Stomach cancer

85

0.03

411

0.04

0.91 (0.72–1.15)

0.96 (0.76–1.22)

 Gynecological cancer

148

0.09

707

0.10

0.91 (0.76–1.09)

1.01 (0.85–1.21)

 Brain cancer

47

0.02

130

0.01

1.55 (1.11–2.17)*

1.78 (1.26–2.51)*

 Urological cancer

150

0.06

471

0.04

1.40 (1.16–1.68)**

1.40 (1.16–1.69)**

 Leukemia

41

0.02

150

0.01

1.20 (0.85–1.69)

1.24 (0.87–1.77)

 Bone cancer

7

0.03+

24

0.02+

1.33 (0.57–3.10)

1.37 (0.57–3.27)

 Nose cancer

74

0.03

181

0.02

1.71 (1.31–2.25)**

1.84 (1.39–2.44)**

  1. a Incidence: incidence density (100 per person-years)
  2. + Incidence: incidence density (1000 per person-years)
  3. *: p <.05, **: p <.001, CHR: crude hazard ratio, AHR: adjusted hazard ratio controlling for age, sex, income, region, urbanization level, and CCI score