Fig. 3

Best clinical response. Waterfall plot showing best clinical response recorded during the planned 6 treatment cycles in the any-dose/safety population. Fourteen of 16 patients are shown; two were omitted from this plot due to incomplete measurements; one with reported stable disease, one with progressive disease. Note two patients, both marked with *, one with stable disease and one with partial response in target lesions are marked as progressive disease as per ACTG criteria due to an increase in (off-target) lesion number. Overall, 1/16 partial response, 11/16 stable disease, 3/16 progressive disease as best response