Fig. 2

Target binding profile of core HPARBPs. (A) Pie chart of target binding genomic regions of the six core HPARBPs. (B) UpSet plot depicting the target genes of the six core HPARBPs. (C) Results of the GO and KEGG functional enrichment analyses of the common targets of the core HPARBPs. Wnt-related terms and pathways are highlighted with red characters. (D) Pie chart displaying the characteristics of Wnt pathway-related genes targeted by the core HPARBPs, providing a detailed view of the regulatory landscape of these genes. (E) Volcano map of Wnt pathway-related genes identified via TCGA-LIHC differential analysis, together with labels of target characteristics