Fig. 2

Oral mucositis and opioid use. The panels in Fig. 2 display overall health (A), and mouth and throat soreness (B), as well as how Mouth and Thorat Soreness limited swallow soreness (C), drinking soreness (D), eating soreness (E), talking soreness (F), sleeping soreness (G), and overall mouth and throat soreness (H) over the previous 24 h, as well as the change in morphine equivalents (I) over the 7-week treatment. OM pain and opioid use during the first seven weeks were analyzed using linear mixed model. The Week 1 scores were considered as baseline. The trajectories estimated by Lowess estimator. Data represents the estimate (SE) and p-values