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Table 3 Relationship between clinical pathological features and ERα expression in HCC (TCGA)

From: Estrogen receptor α suppresses hepatocellular carcinoma by restricting M2 macrophage infiltration through the YAP-CCL2 axis

Characteristics

Low ESR1

High ESR1

χ2

p value

n

187

187

  

Gender, n (%)

  

5.387711103

0.02*

Male

116 (45.8%)

137 (54.2%)

  

Female

71 (58.7%)

50 (41.3%)

  

Age, n (%)

  

8.116021437

0.004*

<= 60

102 (57.6%)

75 (42.4%)

  

> 60

84 (42.9%)

112 (57.1%)

  

Pathologic T stage, n (%)

  

7.264436529

0.026*

T1

80 (43.7%)

103 (56.3%)

  

T2

51 (53.7%)

44 (46.3%)

  

T3&T4

56 (60.2%)

37 (39.8%)

  

Pathologic N stage, n (%)

  

1.930530942

0.165

N0

133 (52.4%)

121 (47.6%)

  

N1

4 (100%)

0 (0%)

  

Pathologic M stage, n (%)

  

1.791825528

0.181

M0

144 (53.7%)

124 (46.3%)

  

M1

4 (100%)

0 (0%)

  
  1. Note The result was analyzed by the Pearson chi-square test. * P < 0.05