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Table 3 Clinical endpoints

From: Procalcitonin-guided antibiotic treatment in patients with cancer: a patient-level meta-analysis from randomized controlled trials

Outcomes

Control group (n = 398)

PCT group (n = 379)

Adjusted OR or difference (95% CI)*, p-value

28- days mortality, n (%)

91 (22.9)

72 (19.0)

0.78 (0.60, 1.02), p = 0.069

Need for ICU care, n (%)

236 (59.3)

241 (63.6)

1.08 (0.98, 1.20), p = 0.125

Antibiotic therapy [days], mean (SD)

9.8 (7.3)

8.2 (6.6)

-1.77 (-2.74, -0.80),p < 0.001

Length of hospital stay [days], mean (SD)

20.9 (18.1)

24.2 (22.5)

1.85 (-0.88, 4.57), p = 0.184

  1. Abbreviations: CI, confidence interval; ICU, intensive care unit; OR, odds ratio; PCT, procalcitonin; SD, standard deviation
  2. *Multivariable hierarchical regression with outcomes of interest as dependent and trail as a random effect
  3. Statistically significant results are diplayed in bold