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Table 2 Results of univariate associations and multivariable Cox models of overall and recurrence free survival in NSCLC patients

From: Skeletal muscle index is associated with long term outcomes after lobectomy for non-small cell lung cancer

Variable

Univariate HR (95% CI)

Multivariable HR (95% CI)

Overall survival

Recurrence free survival

Overall survival

Recurrence free survival

Age

1.04 (1.03–1.06)

1.01 (0.99–1.03)

1.03 (1.01–1.05)

 

Gender

0.52 (0.39–0.68)

0.71 (0.50–1.00)

0.31 (0.21–0.46)

0.5 (0.31–0.81)

 Female vs. Male

Race

 African American vs. Caucasian

0.59 (0.31–1.03)

0.55 (0.23–1.09)

  

 Other vs. Caucasian

1.27 (0.45–2.77)

0.75 (0.12–2.38)

  

DLCO

0.98 (0.98–0.99)

0.99 (0.98–1.00)

0.98 (0.97–0.99)

 

FEV1

0.99 (0.98–0.99)

0.99 (0.98–1.00)

  

ASA score

1.94 (1.47–2.58)

1.32 (0.93–1.87)

1.35 (1.00- 1.82)

 

 High vs. Low

SMI

0.98 (0.97–1.00)

0.99 (0.97–1.00)

0.96 (0.95–0.98)

0.97 (0.95–0.99)

BMI2

1.14 (0.85–1.52)

1.21 (0.84–31.0)

  

Tumor stage

 Stage II vs. Stage I

1.28 (0.94–1.73)

2.18 (1.51–3.13)

 

1.87 (1.17–2.96)

 Stage III vs. Stage I

1.72 (1.06–2.65)

1.74 (0.89–3.10)

2.2 (1.17–3.98)

 

Histology

 Squamous Cell Carcinoma vs. Adenocarcinoma

1.57 (1.17–2.09)

0.97 (0.65–1.42)

  

 Other vs. Adenocarcinoma

1.9 (0.99–3.30)

1.75 (0.78–3.39)

  

Smoking status

 Current vs. Past

0.81 (0.57–1.11)

0.89 (0.58–1.33)

  

 Never vs. Past

0.79 (0.48–1.23)

1.11 (0.63–1.85)

  

Adjuvant Chemotherapy

0.84 (0.61–1.14)

1.61 (1.12–2.29)

  

 Yes vs. No

Adjuvant Radiation

0.96 (0.52–1.62)

1.55 (0.81–2.69

  

 Yes vs. No

  1. Adeno Adenocarcinoma, ASA American society of anesthesiology, DLCO Diffusion capacity of lung for carbon monoxide, FEV1 Forced expiratory volume at 1 s, SCC Squamous cell carcinoma, SMI Skeletal muscle index
  2. 1Multivariable analysis was performed using all variables but only variables that were statistically significant are shown. All statistically significant (P < 0.05) variables are in bold
  3. 2Multivariable analysis for BMI and SMI were performed separately but shown in the same table for ease