Your privacy, your choice

We use essential cookies to make sure the site can function. We also use optional cookies for advertising, personalisation of content, usage analysis, and social media.

By accepting optional cookies, you consent to the processing of your personal data - including transfers to third parties. Some third parties are outside of the European Economic Area, with varying standards of data protection.

See our privacy policy for more information on the use of your personal data.

for further information and to change your choices.
Skip to main content
Fig. 1 | BMC Cancer

Fig. 1

From: CD171- and GD2-specific CAR-T cells potently target retinoblastoma cells in preclinical in vitro testing

Fig. 1

CD171 is expressed in retinoblastomas and cell lines derived from retinoblastomas. a The tumor is composed of small undifferentiated, blue cells (hematoxylin & eosin stain). Flexner-Wintersteiner rosettes may be found and are highly characteristic (arrows). The expression of CD171 was classified as negative or positive. (Scale bar: 50 μm). b CD3+-staining is exemplarily shown for patient 1 and patient 5. CD3+ infiltration in 6 of 30 randomly chosen primary retinoblastoma tumor samples. c CD171 cell surface expression on eleven established retinoblastoma cell lines detected with antihuman fluorochrome-conjugated CD171 antibody (n = 3). d Number of CD171 molecules per cell calculated based on a PE-bead based assay for three selected cell lines, WERI-Rb1, RBL15 and RB355 (mean ± SD, n = 3)

Back to article page

BMC Cancer

ISSN: 1471-2407

Contact us