Fig. 2
From: First case of AML with rare chromosome translocations: a case report of twins
The predicted ZNF273-DGKα fusion. Wild-type ZNF273 contains 13 C2H2 Zn finger domains. Wild-type DGKα contains N-terminal domain, EF hands domain (calcium binding), C1 domain (Phorbol esters/diacylglycerol binding), catalytic domain, and C-terminal domain. The fusion between ZNF273 and DGKα results in the replacement of N-terminal domain of DGKα by C2H2 Zn finger domains of ZNF273