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Table 2 IC50values obtained after 24 h exposure to TPL followed by 72 h incubation in drug free medium. (mean ± s.e.m. of 4–6 independent experiments).

From: Role of the p53/p21 system in the response of human colon carcinoma cells to Doxorubicin

Cell lines

IC25 (μM)

IC50 (μM)

R.I.a

HCT116

280.00 ± 39.21

560.00 ± 77.78

1.0

HT29

320.40 ± 50.03

665.63 ± 102.91

1.19

HCT116 E6

400.06 ± 60.00

837.3 ± 103.99

1.49

HCT116 p21-/-

700.00 ± 99.14

1114.55 ± 182.2

1.99

  1. a The resistance index (R.I.) was calculated as the ratio between the IC50 values obtained for each cell line and that of HCT116 cells
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BMC Cancer

ISSN: 1471-2407

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