Table 6 Colon cancer: the top 10 genes and pair-wise gene expression ratio used to discriminate the colon cancer tissue. This table is ranked with decreasing classification efficiency. The threshold values T i for normal tissues are also provided together with classification efficiency. The list of top 25 genes can be downloaded from http://web.hku.hk/~daniely/microarray.
From: Classification between normal and tumor tissues based on the pair-wise gene expression ratio
Colon Cancer-Original data | Colon Cancer-Transformed data | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
Rank | No. on array | gene accession number | gene info | Threshold for normal tissue type, T j | discriminating efficiency*/% | Ref | Rank | gene number on array | Threshold for normal tissue type, T i | discriminating efficiency*/% | Ref |
1 | #1659 | M26383 | Human monocyte-derived neutrophil-activating protein (MONAP) mRNA, complete cds. | <62.7375 | 87.1% | [12,13] | 1 | #1537/#1831 | <0.75512 | 93.6% | [27,28] |
2 | #753 | M76378 | Human cysteine-rich protein (CRP) gene, exons 5 and 6. | >749.4075 | 83.9% | [26] | 2 | #1831/#1537 | >1.3243 | 93.6% | [27,28] |
3 | #613 | X12671 | Human gene for heterogeneous nuclear ribonucleoprotein (hnRNP) core protein A1. | <233.4162 | 82.3% | [33] | 3 | #1827/#481 | <0.074449 | 91.9% | [14,15,39] |
4 | #569 | T51571 | P24480 CALGIZZARIN. SERINE/THREONINE-PROTEIN | <309.3037 | 77.4% | [34] | 4 | #1537/#1623 | <1.0533 | 91.9% | [27,40] |
5 | #1103 | R97912 | KINASE IPL1 (Saccharomyces cerevisiae) | <70.2738 | 75.8% | [35] | 5 | #1831/#1759 | >1.4003 | 91.9% | [28] |
6 | #1759 | J05032 | Human aspartyl-tRNA synthetase alpha-2 subunit mRNA, complete cds. | <41.92 | 75.8% | [36] | 6 | #1623/#1537 | >0.94939 | 91.9% | [27,40] |
7 | #241 | M63391 | Human desmin gene, complete cds. | >2787.0425 | 75.8% | [17] | 7 | #365/#1760 | >3.3867 | 91.9% | [41,42] |
8 | #818 | R75843 | TRANSLATIONAL INITIATION FACTOR 2 GAMMA SUBUNIT (Homo sapiens) | <152.5662 | 74.2% | [37] | 8 | #1759/#1831 | <0.71414 | 91.9% | [28] |
9 | #1960 | T57468 | FIBRILLARIN (HUMAN). | <42.0225 | 74.2% | [38] | 9 | #1760/#365 | <0.29528 | 91.9% | |
10 | #1281 | H23544 | GTP-BINDING NUCLEAR PROTEIN RNA (Homo sapiens) | <103.2488 | 74.2% | [20] | 10 | #481/#1827 | >13.432 | 91.9% | [14,15,39] |