Figure 4
From: BAK overexpression mediates p53-independent apoptosis inducing effects on human gastric cancer cells

Apoptosis inducing effects of BAK overexpression on gastric cancer cells.
A, Morphological observation of gastric cancer cells under electronic microscope: Normal cells in untransferred group;
Chromatin congregating around nuclear membrane in pcDNA-BAK transferred cancer cells;
Nucleus shrinking in pcDNA-BAK transferred cancer cells. B, Apoptosis detection by TUNEL:
There were no obvious apoptotic cells in the untransferred group;
The pcDNA-BAK transferred cells reduced in size with obvious nuclear staining.