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Table 3 Cirrhosis and methylation profiles of the genes in HCC tissues

From: Methylation profiling of twenty promoter-CpG islands of genes which may contribute to hepatocellular carcinogenesis

Patient

Cirrhosis

Grading

CDH13

p16INK4a

RASSF1A

CASP8

D24

+

III

U

M

M

M

D17

+

III

U

M

M

M

X63

+

II

U

U

M

 

Z89

+

III

U

M

M

M

Z92

+

II

M

M

M

M

D16

+

I

U

U

M

M

Z82

+

I

U

M

M

 

Z85

+

 

U

M

M

 

D15

+

II

U

M

M

M

Z90

+

II

U

M

M

M

D59

+

I

U

M

M

M

G33

+

II

U

U

M

M

G35

+

II

U

M

M

M

G41

+

I

U

M

M

M

G44

+

II

U

U

M

 

G36

+

I

U

M

M

M

Total (%)

C/T(16) 100%

 

M/T(16) 6.25%

M/T(16) 75%

M/T(16) 100%

M/T(12) 100%

D18

-

I

M

U

M

M

Q45

-

II

U

U

M

 

G65

-

III

U

U

M

 

D1

-

I

U

M

M

M

Q47

-

II

M

M

M

M

G63

-

III

U

M

M

M

G64

-

II

U

U

M

 

G47

-

I

U

U

M

M

G62

-

III

M

M

M

M

D14

-

II

U

U

M

M

Q49

-

II

U

U

M

 

Q48

-

I

M

U

M

M

Q46

-

II

M

U

M

 

Total (%)

C/T(13) 0%

 

M/T(13) 38.46%

M/T(13) 30.76%

M/T(13) 100%

M/T(8) 100%