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Table 5 Overall breast cancer survival in relation to serum concentrations of organochlorines by estrogen receptor status.

From: Organochlorine exposures influence on breast cancer risk and survival according to estrogen receptor status: a Danish cohort-nested case-control study

Organochlorines

Estrogen receptor positive

Estrogen receptor negative

in quartiles (ng/mL)

Cases/control

Adjusted RR (95% CI)a

p trendb

Cases/controls

Adjusted RR (95% CI)

p trend

HCB

I

<206.50

13/15

1.0 ref.c

 

7/4

1.0

 

II

206.50-269.75

15/14

0.7 (0.3-1.6)

 

8/3

0.9 (0.3-3.1)

 

III

269.75-335.75

17/12

1.1 (0.5-2.4)

 

3/8

0.2 (0.0-1.2)

 

IV

>335.75

13/15

1.1 (0.5-2.5)

>0.20

4/7

0.2 (0.1-1.7)

0.03

Dieldrin

I

<12.01

8/21

1.0

 

4/7

1.0

 

II

12.01-28.30

17/12

3.4 (1.3-8.7)

 

3/8

0.4 (0.1-3.1)

 

III

28.30-57.11

17/12

2.6 (1.0-6.3)

 

7/4

1.9 (0.5-7.8)

 

IV

>57.11

17/12

2.2 (0.9-5.4)

>0.20

8/3

1.8 (0.3-5.5)

0.06

ΣPCB

I

<811.11

14/15

1.0

 

6/5

1.0

 

II

811.11-1076.04

15/14

1.5 (0.6-3.4)

 

7/4

0.4 (0.1-1.6)

 

III

1076.04-1405.73

13/16

1.0 (0.4-2.3)

 

5/6

0.5 (0.1-2.2)

 

IV

>1405.73

17/12

2.5 (1.1-5.7)

>0.20

4/7

0.1 (0.0-5.6)

0.02

p,p'-DDE

I

<741.04

15/14

1.0

 

6/5

1.0

 

II

741.04-1129.75

13/16

0.7 (0.3-1.6)

 

4/7

0.3 (0.0-2.0)

 

III

1129.75-1688.85

17/12

1.0 (0.5-2.2)

 

5/6

0.7 (0.1-3.7)

 

IV

>1688.85

14/15

1.0 (0.5-2.1)

>0.20

7/4

0.3 (0.1-2.1)

>0.20

  1. a Relative risk of dying, 95% confidence interval, adjusted for age at diagnosis, metastatic lymph nodes, and tumor size; b two sided p-value for linear trend in RR's; c Reference category. Cases with missing information on confounders were excluded.
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BMC Cancer

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