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Figure 5 | BMC Cancer

Figure 5

From: IL-6 signaling by STAT3 participates in the change from hyperplasia to neoplasia in NRP-152 and NRP-154 rat prostatic epithelial cells

Figure 5

Dexamethasone treatment inhibited IL-6 expression in NRP-152 but not NRP-154 cells. Cells were grown in charcoal-adsorbed serum-containing medium prior to beginning dexamethasone treatment (10-6 M) for 2 days. Cells were harvested, fixed, and permeabilized, stained for IL-6, then analyzed for fluorescence in FL2, as described above. Panel A, NRP-152 cells. Panel B, NRP-154 cells. Panel C, NRP-154 clone A3 (high IL-6 – expressing. Panel D, NRP-154 clone G7 (low IL-6-expressing). All panels, purple line = no dexamethasone; red line in panels A & B = + dexamethasone; blue line in panels C & D = + dexamethasone.

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BMC Cancer

ISSN: 1471-2407

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